Liu, a former Olympic champion, is among the leading contenders to win gold at the London Games and he has the perfect opportunity to underline his credentials in the Diamond League meeting at Crystal Palace.
The Chinese star, who leads the world rankings this year with 12.97 seconds, won the Olympic title in Athens in 2004, but left fans devastated when he pulled out of the Beijing Games because of an Achilles injury.
Liu, who turns 29 on Friday, has continued to struggle with injury since Beijing, but he believes he is back to his best after opting for a new stride pattern.
Now, just two weeks before the Games begin, Liu, who also won gold at the 2007 World Championships, hopes to fine-tune his Olympic preparations with victory over outdoor world champion Jason Richardson and world indoor 60m hurdles champion Aries Merritt.
“This will be my last race before the Olympics so I will be looking for a very strong performance. The London Diamond League will be the perfect race for me to complete my preparation,” Liu said.
“I’m really excited to be competing in London for the first time. It’s a great opportunity for me to experience the conditions and atmosphere of the host city just two weeks before the Games.”
After two impressive wins in the Diamond League events in Shanghai and Eugene this year, Liu is hopeful he is on track for success at the Olympics, where his main rival will be Cuban Olympic champion and world record holder Dayron Robles.
“My form has been good so far this season and my preparation is on target,” Liu added.
“The line-up at the London Diamond League is tough and running against world-class athletes in Olympic conditions will be a good test for me.
“I really enjoy racing in the UK, although I have not had many chances in my career. Hopefully I will have a lot of support from the Chinese community.”
With 16 Olympic and 15 reigning World Champions taking to the track this Friday and Saturday there are plenty of intriguing events, but the main highlight will be the 100m clash between injury-prone duo Tyson Gay and Asafa Powell.
The second and third fastest men of all time will take to the track in south London hoping to prove they still have Olympic gold medal potential despite the dominance of Usain Bolt and Yohan Blake.
American star Gay won the US trials last week in a respectable 9.86 seconds, while Powell, the former world record holder, finished third behind Blake and Bolt in the Jamaican trials.
While Blake and Bolt look to be in a league of their own — clocking 9.75secs and 9.76secs this year — Gay and Powell are determined to lay down markers of their own in London.
Meanwhile, the clash of the second fastest woman of all-time, Carmelita Jeter, with new Jamaican record holder Shelly-Ann Fraser-Pryce over 100m will be one to watch on Saturday.