Brighter news for Giggs is that star player Gareth Bale will return to the starting line-up, having sat out the friendly.
Ethan Ampadu, Sam Vokes and Tom Lawrence are sitting the qualifying match out due to injuries.
Giggs has a record of three wins, one draw and five defeats from his nine games in charge.
Bale has won four Champions League trophies in Spain but has been consistently relegated to the bench in recent weeks.
The suspension comes as Hitachi's Horizon Nuclear Power failed to find private investors for its plans to build a plant in Anglesey.
The subversive artist confirmed on Instagram that the "Season's Greetings" mural on a breeze block garage wall was genuine.
For MPs preparing for a vote on whether or not to back Prime Minister Theresa May's Brexit deal, views in places like Wales will be paramount.
Wales coach Warren Gatland believes that Gareth Anscombe could start at flyhalf for Wales against Scotland.
In the opening stages in Dublin, Giggs's young side were a pale shadow of the team that ripped apart Ireland in Cardiff last month, with Real Madrid forward Bale and Arsenal midfielder Ramsey among the goals.
Gareth Bale, who will miss Wales's Nations League game against Ireland, will be replaced by Gwion Edwards.
Wales coach Ryan Giggs expects Gareth Bale to miss the team's Nations League clash against Ireland because of a groin injury.
Paco Alcácer continued his rampant form by scoring a goal for the fifth consecutive game.
Gareth Bale's groin injury will keep him out of Wales's game against Spain.
Koke and Álvaro Morata were recalled to the Spain squad for internationals against Wales and England, but Diego Costa was not.
Christian Eriksen scored both goals in Denmark's 2-0 Nations League victory over Wales.
Gareth Bale will continue to be the star of Ryan Giggs's Wales team, which is due to play matches against Ireland and Denmark.
Hal Robson-Kanu leaves the Wales team after eight years.
Researchers revealed that many probably came from as far as Wales, source of the bluestone used to carve Stonehenge's mysterious and entrancing monuments.
Gordon Langkilde was benched for Samoa's games in the consolation rounds after a stormy end to Wales' 24-19 win over the South Pacific islanders on Saturday.
Sam Warburton retired after having played 74 games for Wales.
As Theresa May sets off on a nationwide tour, the United Kingdom continues to be divided over Brexit.
The British royal family has been using wedding rings made of Welsh gold for almost a century.
The deal would resolve a deadlock over Scotland and Wales's post-Brexit powers.
After beating Italy, Warren Gatland's Wales team can clinch second place in this year's Six Nations by beating France.
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