
The key Nikkei 225 index slipped 0.18% or 44.12 points to 24,226.50 in early trade, while the broader Topix index was down 0.15% or 2.67 points at 1,821.36.
“Profit-taking sales are growing and we will likely see a lull in Japanese shares,” Okasan Online Securities said in a commentary.
“While the yen’s depreciation has slowed after it touched the 114 yen level (against the dollar earlier this week), there are few other market-moving events,” it noted.
Investors were also awaiting key US jobs data due this weekend, analysts said.
The dollar fetched ¥113.59 in early Asian trade, against ¥113.68 in New York late Tuesday.
In Tokyo, blue-chip exporters were lower, with Toyota trading down 1.39% at ¥7,075, Honda 2.66% at ¥3,393, Sony off 1.62% at ¥6,725 and Panasonic down 1.67% at ¥1,348.5.
In New York, the Dow closed up 0.5% at a fresh record of 26,773.94.