
FBI agents surrounded Maduro as he descended from a US government plane and slowly escorted him along the tarmac at a National Guard facility in New York state.
The leftist leader was then flown by helicopter to Manhattan, where a large law enforcement contingent awaited, AFP images showed.
The 63-year-old leader was to be taken first to the offices of the US Drug Enforcement Administration, then to the Metropolitan Detention Center, a federal facility in Brooklyn, according to US media.
The detention centre is the same jail where rapper Sean “Diddy” Combs was held throughout his trial last year.
Maduro and his wife are to be arraigned at an unspecified date before a judge in New York. They have been charged with “narco-terrorism”, importing tonnes of cocaine into the US, and possession of illegal weapons.