The 16-year-old, who made history in September when he became the youngest-ever player to score for Spain’s national team, left the camp after medical personnel “determined he could not participate in the next two qualifying matches,” the federation said in a statement.

Yamal had been in doubt after Barcelona announced the teenager had suffered a hip flexor problem during the Catalan side’s 2-2 draw with Granada in La Liga.

He became La Liga’s youngest-ever goalscorer during the match at 16 years and 87 days when he scored just before half-time.

Yamal was spotted limping yesterday as he joined up with Spain’s national team.

Barcelona’s night was also marred by a knee injury to Jules Kounde, with the Catalans already tending to Robert Lewandowski, Frenkie de Jong, Pedri, and Raphinha in the treatment room.

Yamal became Barcelona’s youngest debutant at 15 years and 290 days old against Real Betis in April last season.

This season, Yamal went on to become La Liga’s youngest starter in the 21st century, and also the youngest assist provider in the same timeframe.

He extended his contract with Barcelona until 2026 earlier in October, with a €1 billion release clause.